In a large study of 400 people with HIV-related belly fat, tesamorelin reduced visceral fat by nearly 11% after 6 months, compared to less than 1% in the placebo group, and also reduced waist and trunk fat while increasing IGF-1 levels.

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Evidence from Studies

Supporting (3)

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Effects of Tesamorelin, a Growth Hormone–Releasing Factor, in HIV-Infected Patients With Abdominal Fat Accumulation: A Randomized Placebo-Controlled Trial With a Safety Extension

Randomized Controlled Trial

Human

2010 Mar

This study found that a drug called tesamorelin helped HIV patients lose belly fat, shrink their waist, and boost a helpful hormone—without harming their blood sugar—while a dummy pill did almost nothing.

1499. Tesamorelin Reduces Visceral Adipose Tissue and Liver Fat in INSTI-Treated Persons with HIV

Randomized Controlled Trial

Human

This study shows that tesamorelin helps reduce belly fat in people with HIV, which matches the claim.

Visceral fat reduction with tesamorelin is associated with improved liver enzymes in HIV

Randomized Controlled Trial

Human

2017 Oct 23

Tesamorelin not only reduces belly fat but also improves liver health in people with HIV.

Contradicting (0)

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No contradicting evidence found

Similar Assertions

A hormone treatment called tesamorelin decreases belly fat by 42 square centimeters more than a placebo in people with HIV who have excess abdominal fat after six months of treatment.

95%

A drug called tesamorelin helps HIV patients with belly fat buildup lose about 11% of their dangerous internal belly fat in six months, while those on a dummy pill lose almost none.

94%

A drug called tesamorelin helps reduce belly fat deep inside the abdomen for people with HIV who are on medication, making their belly fat decrease by about 15% compared to those not taking the drug. This finding is from the abstract summary - full study details were not available

94%

Continuing tesamorelin for a full year helps HIV patients with belly fat lose nearly 18% of their dangerous internal belly fat, with no loss of benefit over time.

93%

A hormone treatment called tesamorelin doesn't change the fat under the skin in people with HIV who have excess belly fat after six months of treatment.

92%