The Claim
In patients with ST-elevation myocardial infarction, polyphenol supplementation is associated with a reduction in the abundance of Parabacteroides goldsteinii and Lactobacillus salivarius, microbial taxa previously associated with trimethylamine N-oxide production and lipid metabolism.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In patients who have had a heart attack called STEMI, taking polyphenol supplements is linked to lower levels of two gut bacteria, Parabacteroides goldsteinii and Lactobacillus salivarius, which have been connected to the production of trimethylamine N-oxide and lipid metabolism.
See the scientific wording
In STEMI patients, polyphenol supplementation is associated with a decrease in the abundance of Parabacteroides goldsteinii and Lactobacillus salivarius, taxa previously linked to TMAO production and lipid metabolism, suggesting a selective suppression of potentially detrimental microbes.
Polyphenols feed beneficial gut bacteria that make butyrate, which strengthens the gut lining and outcompetes harmful bacteria that produce TMAO. This stops TMAO from rising in the blood, reducing damage to the heart and blood vessels.
What the research says
1 studyStudy: Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study
In heart attack patients, taking polyphenol supplements lowered one harmful gut bacterium (Parabacteroides goldsteinii) and kept a dangerous blood chemical (TMAO) from rising, which suggests the supplements may help by cleaning up bad gut bacteria linked to heart disease.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.