In kids who got a kidney transplant and are on a certain anti-rejection drug combo, taking more or less of one drug (mycophenolic acid) doesn’t change how the body handles another drug (sirolimus).

36

Pro

0

Against

Evidence from Studies

Supporting (1)

36

Community contributions welcome

36

Short sirolimus half‐life in pediatric renal transplant recipients on a calcineurin inhibitor‐free protocol

Cross-Sectional Study

Human

2004 Apr

The study looked at kids with kidney transplants taking sirolimus and mycophenolate, and found that one drug didn’t affect how the body processed the other, just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Short sirolimus half‐life in pediatric renal transplant recipients on a calcineurin inhibitor‐free protocol

Score: 36

DOI: 10.1046/j.1399-3046.2003.00148.x

Similar Assertions

For kids who've had a kidney transplant and are taking a drug called sirolimus (but not certain other drugs), checking the lowest level of the drug in their blood helps doctors figure out how much of the drug their body is getting overall.

36

0

82%