In mice, being exposed to a chemical called BDE-47 might cause their livers to store more fat and not burn it properly, leading to fatty liver and signs of liver damage — a possible early sign of a liver disease linked to metabolism problems.

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Evidence from Studies

Supporting (1)

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BDE-47 induces metabolic dysfunction-associated steatotic liver disease (MASLD) through CD36-mediated increased fatty acid uptake and PPARα-induced abnormal fatty acid oxidation in BALB/c mice.

Cross-Sectional Study

Animal

2024 Jan

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No contradicting evidence found

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Source Study

BDE-47 induces metabolic dysfunction-associated steatotic liver disease (MASLD) through CD36-mediated increased fatty acid uptake and PPARα-induced abnormal fatty acid oxidation in BALB/c mice.

Score: 6

DOI: 10.1016/j.toxlet.2023.11.006

Similar Assertions

When these lab mice are exposed to a chemical called BDE-47, it might slow down their liver's ability to burn fat, leading to fat buildup that could cause a type of liver disease.

83%

In these lab mice, a chemical called BDE-47 turns up a protein that pulls more fat into the liver, which can lead to fatty liver disease.

81%