mechanistic
Analysis v1
Strong Support
In mice with a kidney disease similar to one in humans, giving them a drug called fenofibrate seems to boost the activity of genes that help burn fat for energy in the kidneys, which might mean their kidney cells are using energy more efficiently.
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0
Evidence from Studies
Supporting (1)
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Community contributions welcome
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PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice.
Randomized Controlled Trial
Animal
2018 Jan 1The study gave fenofibrate to kidney disease mice and found it boosted fat-burning and energy production in their kidneys, just like the claim says.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.