Fenofibrate, a drug that changes how the liver processes energy, seems to help reduce liver cysts and damage in a type of mouse with a genetic liver disease.

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Evidence from Studies

Supporting (1)

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PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice.

Randomized Controlled Trial

Animal

2018 Jan 1

Contradicting (0)

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No contradicting evidence found

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Source Study

PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice.

Score: 12

DOI: 10.1152/ajprenal.00352.2017

Similar Assertions

In mice with a genetic form of kidney disease, taking a drug called fenofibrate seems to slow down the growth of kidney cysts and reduce harmful inflammation in the kidneys.

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In mice with a kidney disease similar to one in humans, giving them a drug called fenofibrate seems to boost the activity of genes that help burn fat for energy in the kidneys, which might mean their kidney cells are using energy more efficiently.

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Fenofibrate seems to slow down kidney disease in mice with a condition similar to polycystic kidney disease, making their kidneys healthier after five months of treatment.

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