The Claim

In obese men, an 8-week combination of resistance exercise training and alternate-day calorie restriction results in greater increases in circulating levels of adipsin and soluble epidermal growth factor receptor (sEGFR) than resistance exercise training alone or alternate-day calorie restriction alone.

Source: Comparative effects of 8-week combined resistance exercise training and alternate-day calorie restriction on soluble epidermal growth factor receptor (sEGFR) and adipsin in obese men

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
26score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

In obese men, combining 8 weeks of strength training with alternate-day fasting increases blood levels of adipsin and sEGFR more than either approach by itself.

See the scientific wording

In obese men, an 8-week combination of resistance exercise training and alternate-day calorie restriction leads to greater improvements in circulating levels of adipsin and soluble epidermal growth factor receptor (sEGFR) compared to either intervention alone.

Why this might work

When obese men do strength training and skip calories every other day, their fat tissue shrinks and releases more adipsin, while the skin-like layer around cells sheds more of its receptor, increasing its presence in the blood.

Suggested mechanismbased on 1 study

What the research says

1 study
  1. Study: Comparative effects of 8-week combined resistance exercise training and alternate-day calorie restriction on soluble epidermal growth factor receptor (sEGFR) and adipsin in obese men

    In obese men, doing both weight training and skipping calories every other day worked better than doing just one of those things alone — it improved two important blood markers more than either method by itself.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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