The Study
Comparative effects of 8-week combined resistance exercise training and alternate-day calorie restriction on soluble epidermal growth factor receptor (sEGFR) and adipsin in obese men
We don't know how the study was done — maybe they picked people randomly, maybe not. So we can't say for sure that the exercise and diet caused the changes we saw. It might just be coincidence or something else.
Analysis score
Maximum 90 for a randomized controlled trial.
Where the score came from
When obese men lifted weights and ate fewer calories every other day, they lost more fat and improved their health markers better than doing just one of those things alone.
Where does this study sit?
Reviews of RCTs (Meta-analyses)
Max 100Randomized Trials
Max 90Reviews of Cohort Studies
Max 85Cohort Studies
Max 72Reviews of Case-Control Studies
Max 63Case-Control Studies
Max 58Cross-Sectional & Case Series
Max 50Expert Opinion
Max 526 / 100
Quality score
Participants are randomly assigned to treatment or control groups, minimizing bias. The gold standard for testing whether an intervention causes an effect.
Key takeaways
Summary
Based on the study abstract and findings.
- 1Yes — losing more fat and improving insulin resistance can lower diabetes and heart disease risk, which matters for long-term health.
- 2They lost more weight, body fat, and waist size; their insulin resistance improved; and two key blood proteins (adipsin and sEGFR) changed favorably.
Score breakdown, methodology, conflicts of interest, evidence analysis & raw study data
Publication
Journal
Growth Factors
Year
2024
Authors
Yousif Hikmat, A. Safarzade, Hamid Alizadeh
Related Content
Claims (4)
When people reduce their calorie intake, adding resistance training leads to more fat loss than reducing calories alone.
In obese men, combining resistance training with alternate-day calorie restriction for eight weeks leads to larger decreases in body weight, body fat, and waist-to-hip ratio than using either method by itself.
In obese men, combining resistance training with alternate-day calorie restriction for eight weeks leads to larger reductions in insulin resistance than either approach by itself.
In obese men, combining 8 weeks of strength training with alternate-day fasting increases blood levels of adipsin and sEGFR more than either approach by itself.
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.