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correlational
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In people with chronic fatigue syndrome, those with specific antibodies against selenoprotein P show lower levels of a combined measure of thyroid hormone activation and iodine intake than those...

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Evidence from Studies

Supporting (1)

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Autoantibodies to selenoprotein P in chronic fatigue syndrome suggest selenium transport impairment and acquired resistance to thyroid hormone

Case-Control Study
Human
2023 Sep

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Source Study

Autoantibodies to selenoprotein P in chronic fatigue syndrome suggest selenium transport impairment and acquired resistance to thyroid hormone

Score: 54
DOI: 10.1016/j.redox.2023.102796

Similar Assertions

People with chronic fatigue syndrome who have autoantibodies targeting selenoprotein P show lower levels of markers indicating thyroid hormone conversion to its active form, compared to those without these autoantibodies.

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91%

People with chronic fatigue syndrome who have specific antibodies targeting selenoprotein P excrete less iodine in their urine than those without these antibodies or healthy individuals, suggesting a reduction in the release of iodide from thyroid hormones caused by decreased deiodinase enzyme function.

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87%

People taking synthetic thyroid hormone (levothyroxine) for thyroid conditions show lower levels of a specific enzyme activity that converts T4 to T3 in the body, compared to people whose thyroid glands overproduce hormones due to Graves' disease or a toxic nodule.

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71%