The Claim
In adults with type 2 diabetes, elevated postprandial glucagon-to-C-peptide index ratios are associated with elevated average glucose levels, suggesting that relative glucagon excess contributes to sustained hyperglycemia independent of insulin deficiency.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
In adults with type 2 diabetes, higher ratios of glucagon to C-peptide after meals are linked to higher average blood glucose levels, indicating that excess glucagon relative to insulin production contributes to persistently high blood sugar.
See the scientific wording
In adults with type 2 diabetes, higher postprandial glucagon-to-C-peptide index ratios are associated with higher average glucose levels, indicating that relative glucagon excess may contribute to sustained hyperglycemia beyond insulin deficiency.
After eating, the pancreas releases too much glucagon and not enough insulin, causing the liver to make and release more sugar into the blood than needed, which keeps blood sugar levels high for longer.
What the research says
1 studyStudy: 77-OR: Time in Range Is Associated with Glucagon/C-Peptide Index Ratio in Type 2 Diabetes Patients
In people with type 2 diabetes, when the hormone glucagon is high compared to insulin after eating, their blood sugar tends to stay higher and swing more — this study found that link clearly.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.