The Claim

Cyclocreatine transport in C6 rat glioma cells is mediated by an active, sodium-dependent mechanism that follows Michaelis-Menten kinetics, and this transport is reduced by more than fivefold under low-glucose conditions, suggesting dependence on cellular energy status or glucose availability.

Source: Cyclocreatine transport and cytotoxicity in rat glioma and human ovarian carcinoma cells: 31P-NMR spectroscopy.

What the research says

Roughly balanced

Support and challenge are close. The picture may shift as more studies come in.

Supports
6score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In rat brain tumor cells, a substance called cyclocreatine gets pulled in using energy and sodium, but when sugar levels drop, this process slows down a lot—showing it needs energy from sugar to work well.

See the scientific wording

Cyclocreatine transport in C6 rat glioma cells occurs via an active, sodium-dependent mechanism exhibiting Michaelis-Menten kinetics, and this transport is reduced more than fivefold in low-glucose conditions, indicating dependence on cellular energy status or glucose availability.

What the research says

1 study

  1. Study: Cyclocreatine transport and cytotoxicity in rat glioma and human ovarian carcinoma cells: 31P-NMR spectroscopy.

    The study shows that cyclocreatine enters rat brain tumor cells using a specific energy-powered process that needs sodium and gets much slower when sugar is low, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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