Analysis Version
v1
History
Back to Study: Ketone body 3-hydroxybutyrate elevates cardiac out...
causal
Analysis v1
14
Pro
0
Against

In rats, a ketone body reduced resistance in blood vessels without changing overall blood pressure.

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

definitive

Can make definitive causal claims

Assessment Explanation

The in vivo hemodynamic measurements with controlled interventions support definitive causal language for the specific experimental conditions.

Evidence from Studies

Supporting (1)

14
14

Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility

Randomized Controlled Trial
Animal
2023 Sep 9

Contradicting (0)

0
No contradicting evidence found

Source Study

Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility

Score: 14
DOI: 10.1007/s00395-023-01008-y

Similar Assertions

In rats, a ketone body made the heart contract more forcefully, as shown by faster pressure changes in arteries.

14
0
82%

In rats, a specific dose of a ketone body made the heart pump more blood per beat and overall without changing how fast the heart beats.

14
0
77%