In rats, a specific dose of a ketone body made the heart pump more blood per beat and overall without changing how fast the heart beats.

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Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility

Randomized Controlled Trial

Animal

2023 Sep 9

0

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No contradicting evidence found

In rats, a ketone body made the heart contract more forcefully, as shown by faster pressure changes in arteries.

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83%

In rats, a ketone body reduced resistance in blood vessels without changing overall blood pressure.

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77%

When added to isolated rat hearts, a ketone body made the heart muscle contract more strongly and increased blood flow to the heart muscle itself.

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70%