quantitative
Analysis v1
17
0
In rats with heart injury from blocked blood flow, butyrate at a certain dose reduced the damaged heart tissue by 81.7%.
Scientific Claim
In rats subjected to ischemia-reperfusion injury, butyrate at 5 mM was associated with an 81.7% reduction in myocardial infarct size compared to control.
Original Statement
“reducing myocardial infarct size by 81.7±16.9%.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study is an animal model with no human data, so 'associated with' is correct. The verb strength is appropriate as the study design (animal cohort) cannot establish causation.
Evidence from Studies
Supporting (1)
17
17
Short‐Chain Fatty Acid Butyrate Is an Inotropic Agent With Vasorelaxant and Cardioprotective Properties
Randomized Controlled Trial
Animal
2024 May 7Contradicting (0)
0
No contradicting evidence found