In rat hearts, butyrate at a higher dose increased blood flow through the heart's arteries by 20.9%.

In rat hearts outside the body, butyrate at a certain dose made the heart pump harder, increasing pressure by 14.1%.

In rats, giving butyrate at a certain concentration made the heart pump 48.8% more blood without changing blood pressure or heart rate.

In rats, butyrate caused blood vessels in the heart to relax more as the dose increased, with the most effective dose being 0.57 mM.

In rats, butyrate made blood vessels wider, reducing resistance by 33.5% without changing blood pressure or heart rate.

In rats with heart injury from blocked blood flow, butyrate at a certain dose reduced the damaged heart tissue by 81.7%.