quantitative
Analysis v1
17
0
In rat hearts, butyrate at a higher dose increased blood flow through the heart's arteries by 20.9%.
Scientific Claim
In isolated rat hearts, butyrate at 5 mM was associated with a 20.9% increase in coronary flow rate compared to control.
Original Statement
“increased coronary flow rate in hearts mounted in Langendorff systems (20.9±7.1% at 5 mM)”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The study is an animal model with no human data, so 'associated with' is correct. The verb strength is appropriate as the study design (animal cohort) cannot establish causation.
Evidence from Studies
Supporting (1)
17
17
Short‐Chain Fatty Acid Butyrate Is an Inotropic Agent With Vasorelaxant and Cardioprotective Properties
Randomized Controlled Trial
Animal
2024 May 7Contradicting (0)
0
No contradicting evidence found