In this short study, atorvastatin didn’t cause serious side effects in people with high cholesterol, making it safe enough to consider for treatment.

Pro

Against

Evidence from Studies

Supporting (1)

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Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor.

Randomized Controlled Trial

Human

1995 May

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor.

Score: 57

DOI: 10.1161/01.ATV.15.5.678

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