The Claim

Among recreationally active young men undergoing 8 weeks of leg extension resistance training, 40% of individuals taking a supplement blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract exceed the minimal important difference for vastus intermedius cross-sectional area, while 0% of individuals in the placebo group exceed this threshold.

Source: Effects of supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract on training-induced changes in leg extension strength, endurance, and muscle size

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
53score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

In young men doing leg exercises for 8 weeks, 40% of those taking a specific supplement blend showed a muscle growth change large enough to be considered meaningful, while none of those taking a placebo did.

See the scientific wording

In recreationally active young men undergoing 8 weeks of leg extension resistance training, the minimal important difference (MID) for vastus intermedius cross-sectional area is exceeded by 40% of individuals taking a supplement blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract, compared to 0% in the placebo group.

Why this might work

The supplement blend allows muscles to work harder during training by maintaining energy and reducing fatigue, which triggers stronger growth signals. It also blocks the body's natural cleanup process that breaks down muscle, so more muscle tissue builds up, especially in the deep thigh muscle.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract on training-induced changes in leg extension strength, endurance, and muscle size

    In a study with young men doing leg workouts, 4 out of 10 who took a special supplement blend saw a meaningful increase in one thigh muscle, while none of those who took a fake pill did. So the supplement worked for some people, just like the claim says.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.