The Claim

In recreationally active young men undergoing 8 weeks of leg extension resistance training, supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract (TCLB) increases the cross-sectional area of the vastus intermedius muscle by approximately 5.4% and total quadriceps cross-sectional area by approximately 3.9% compared to placebo, without improving strength or endurance outcomes.

Source: Effects of supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract on training-induced changes in leg extension strength, endurance, and muscle size

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
53score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Quantitative
1 study reviewed
In plain English

In young men doing leg extension exercises for 8 weeks, taking a supplement containing trisodium citrate, creatine monohydrate, leucine, and blueberry extract increases the size of the vastus intermedius muscle by 5.4% and the total quadriceps muscle by 3.9% compared to a placebo, but does not improve strength or endurance.

See the scientific wording

In recreationally active young men undergoing 8 weeks of leg extension resistance training, supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract (TCLB) likely increases the cross-sectional area of the vastus intermedius muscle by approximately 5.4% and total quadriceps cross-sectional area by approximately 3.9% compared to placebo, without improving strength or endurance outcomes.

Why this might work

The supplement helps muscles grow bigger by keeping the muscle environment less acidic during workouts, giving cells more energy to work harder, turning on signals that build muscle proteins, and turning off signals that break down muscle tissue — especially in the deepest thigh muscle.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract on training-induced changes in leg extension strength, endurance, and muscle size

    In young men doing leg extensions for 8 weeks, taking this special supplement made one deep thigh muscle and the whole quadriceps group slightly bigger than taking a placebo — but didn’t make them stronger or help them do more reps.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

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