The Claim

In recreationally active young men undergoing 8 weeks of leg extension resistance training, supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract (TCLB) does not significantly improve leg extension strength or endurance compared to placebo or creatine monohydrate.

Source: Effects of supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract on training-induced changes in leg extension strength, endurance, and muscle size

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
53score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

In young men who exercise regularly, taking a supplement containing trisodium citrate, creatine monohydrate, leucine, and blueberry extract for 8 weeks during leg extension training does not result in greater gains in leg strength or endurance than taking a placebo or creatine monohydrate alone.

See the scientific wording

In recreationally active young men undergoing 8 weeks of leg extension resistance training, supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract (TCLB) does not significantly improve leg extension strength or endurance compared to placebo or creatine monohydrate.

Why this might work

The supplement blend increases muscle size by boosting protein building and reducing muscle breakdown, but this extra muscle does not make the muscles stronger or more enduring because the nervous system does not learn to use the new muscle fibers more effectively during exercise.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of supplementation with a blend of trisodium citrate, creatine monohydrate, leucine, and blueberry extract on training-induced changes in leg extension strength, endurance, and muscle size

    The study found that taking the fancy supplement didn't make young men stronger or let them do more reps than taking just creatine or a sugar pill — even though it made one thigh muscle a little bigger.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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