The Claim

In young adult males undergoing a 5-day energy deficit of approximately 30% below maintenance, consuming 0.3 g/kg of essential amino acids (23.5 g) post-resistance exercise increases whole-body protein synthesis by 3.4 g/180 min and reduces protein breakdown by 15.6 g/180 min compared to 0.1 g/kg (7.87 g), resulting in a more positive net protein balance, despite no difference in mixed muscle protein synthesis rates.

Source: Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study.

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
72score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

How it works
1 study reviewed
In plain English

In young adult males with a 30% energy deficit over five days, consuming 23.5 grams of essential amino acids after resistance exercise increases whole-body protein synthesis by 3.4 grams per 180 minutes and decreases protein breakdown by 15.6 grams per 180 minutes compared to 7.87 grams, leading to a more positive net protein balance, with no change in muscle protein synthesis rates.

See the scientific wording

In young adult males undergoing a 5-day energy deficit of approximately 30% below maintenance, consuming 0.3 g/kg of essential amino acids (23.5 g) post-resistance exercise increases whole-body protein synthesis by 3.4 g/180 min and reduces protein breakdown by 15.6 g/180 min compared to 0.1 g/kg (7.87 g), resulting in a more positive net protein balance, despite no difference in mixed muscle protein synthesis rates.

Why this might work

When a person eats a large amount of essential amino acids after working out while eating fewer calories, the blood carries more of these building blocks to the body's tissues. This triggers the body to make more protein overall and stop breaking down as much protein, leading to a net gain in protein. This happens even though the muscles themselves don't make more protein than when fewer amino acids are eaten.

Verified mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study.

    When young men eat a lot of essential amino acids (23.5 grams) after working out while eating less food, their body builds more protein and breaks down less of it overall — even though their muscles don’t make more protein than when they eat less amino acids (7.87 grams).

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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