In healthy young men, introducing fat directly into the upper intestine increased a hormone linked to fullness but did not lead to a meaningful reduction in how much they ate.

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Effect of a protein preload on food intake and satiety feelings in response to duodenal fat perfusions in healthy male subjects.

Randomized Controlled Trial

Human

2005 Oct

Contradicting (0)

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No contradicting evidence found

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Effect of a protein preload on food intake and satiety feelings in response to duodenal fat perfusions in healthy male subjects.

Score: 56

DOI: 10.1152/AJPREGU.00039.2005

Similar Assertions

When healthy young men consume protein before a meal and fat is delivered directly to the upper intestine, the total amount of food they eat is not lower than when they consume protein alone. This suggests the two stimuli affect fullness independently, not together.

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