Insulin helps open up blood vessels in your muscles, letting more blood through so nutrients like creatine can get to the muscle cells more easily.
Evidence from Studies
Supporting (3)
Community contributions welcome
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release.
The study shows insulin helps widen blood vessels in muscle using nitric oxide, which increases blood flow. But it doesn’t test whether this actually helps more creatine get into the muscles.
Insulin resistance in essential hypertension is characterized by impaired insulin stimulation of blood flow in skeletal muscle
The study shows that insulin increases blood flow to muscles, which supports the idea that it helps deliver nutrients like creatine more effectively.
Muscle microvascular blood flow responses in insulin resistance and ageing
The study shows insulin helps increase blood flow to muscles, which can help deliver nutrients, but it didn’t look at creatine specifically.
Contradicting (0)
Community contributions welcome
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.