Why insulin doesn't work as well in high blood pressure
Insulin resistance in essential hypertension is characterized by impaired insulin stimulation of blood flow in skeletal muscle
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Insulin helps blood flow and sugar use in muscles. In people with slightly high blood pressure, insulin doesn't increase blood flow or sugar use as much as in healthy people.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 527 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Insulin helps blood flow and sugar use in muscles. In people with slightly high blood pressure, insulin doesn't increase blood flow or sugar use as much as in healthy people.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 527 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Laine H, Knuuti MJ, Ruotsalainen U, Raitakari M, Iida H, Kapanen J, Kirvelä O, Haaparanta M, Yki-Järvinen H, Nuutila P
Related Content
Claims (4)
Insulin helps open up blood vessels in your muscles, letting more blood through so nutrients like creatine can get to the muscle cells more easily.
People with mild high blood pressure don't get as big of a blood flow boost in their muscles when insulin kicks in, compared to people with normal blood pressure.
People with mild high blood pressure who aren't taking medicine don't process sugar as well in their muscles and body when insulin is high, which suggests their body is resisting insulin's effects.
People with mild high blood pressure who have trouble using insulin well also tend to have muscles that don’t take in sugar properly and don’t get as much blood flow — suggesting their metabolism and blood vessels might be struggling together.