Higher levels of a substance called lithocholic acid in the blood might mean better survival for people with chronic liver disease — one study found that patients with levels above 0.32 had better...

Pro

Against

Evidence from Studies

Supporting (1)

Community contributions welcome

Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans

Cross-Sectional Study

Human & Animal & In Vitro

2022 Oct 7

Contradicting (0)

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans

Score: 51

DOI: 10.7554/eLife.80638

Similar Assertions

In people with long-term liver disease, having more of a certain gut-related acid in the blood might be linked to having more leg muscle strength — and this acid could help doctors spot muscle loss early.

72%