descriptive
Analysis v1
16
0
Mice with extra kidney lymphatic vessels on a high-salt diet had more of a hormone that helps the body get rid of salt and water.
Scientific Claim
During chronic salt loading, mice with kidney-specific lymphangiogenesis exhibited higher plasma atrial natriuretic peptide levels compared to controls.
Original Statement
“KidVD+ mice had a significant increase in plasma ANP levels, only when challenged with chronic sodium (Fig. 4k).”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The claim uses 'exhibited higher' which is appropriate for an association in an animal study, as causation cannot be established.
Evidence from Studies
Supporting (1)
16
16
Kidney-specific lymphangiogenesis increases sodium excretion and lowers blood pressure in mice.
Randomized Controlled Trial
Animal
2020 MayContradicting (0)
0
No contradicting evidence found