How kidney lymph vessels help lower blood pressure
Kidney-specific lymphangiogenesis increases sodium excretion and lowers blood pressure in mice.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
No differences in renal immune cells despite blood pressure changes
Prior research linked immune cells to hypertension, but this study showed lymphatics reduced blood pressure without altering immune cells.
Practical Takeaways
Monitor salt intake to reduce hypertension risk
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Surprising Findings
No differences in renal immune cells despite blood pressure changes
Prior research linked immune cells to hypertension, but this study showed lymphatics reduced blood pressure without altering immune cells.
Practical Takeaways
Monitor salt intake to reduce hypertension risk
Publication
Journal
Journal of Hypertension
Year
2020
Authors
Dakshnapriya Balasubbramanian, G. Baranwal, Mary-Catherine C Clark, Bethany L Goodlett, B. Mitchell, J. Rutkowski
Related Content
Claims (10)
Kidneys regulate blood volume by controlling sodium and water excretion.
When mice ate a high-salt diet, growing more lymphatic vessels in their kidneys lowered their blood sodium levels by about 4% compared to mice without extra lymphatic vessels.
Mice with extra kidney lymphatic vessels on a high-salt diet excreted 64% more sodium in their urine compared to normal mice, helping them manage salt better.
Growing more lymphatic vessels in mouse kidneys during high-salt intake doubled the amount of fluid in the kidney tissue, acting like a sponge to hold extra fluid.
Mice with extra kidney lymphatic vessels on a hypertension-inducing drug excreted more sodium relative to their kidney function compared to normal mice.