quantitative
Analysis v1
16
0
Growing more lymphatic vessels in mouse kidneys during high-salt intake doubled the amount of fluid in the kidney tissue, acting like a sponge to hold extra fluid.
Scientific Claim
Kidney-specific lymphangiogenesis in mice during chronic salt loading was associated with a nearly two-fold increase in renal tissue fluid volume.
Original Statement
“An intriguing finding of this study is that augmenting renal lymphatics increases renal tissue fluid volume by almost two-fold specifically during a chronic salt load.”
Evidence Quality Assessment
Claim Status
appropriately stated
Study Design Support
Design supports claim
Appropriate Language Strength
association
Can only show association/correlation
Assessment Explanation
The claim uses 'associated with' and references the study's own description of 'almost two-fold', which is appropriate for this exploratory animal study.
Evidence from Studies
Supporting (1)
16
16
Kidney-specific lymphangiogenesis increases sodium excretion and lowers blood pressure in mice.
Randomized Controlled Trial
Animal
2020 MayContradicting (0)
0
No contradicting evidence found