A drug called evolocumab blocks PCSK9 and can lower bad cholesterol by over 80% when added to statins.

Pro

Against

Evidence from Studies

Supporting (3)

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Effects of AMG 145 on low-density lipoprotein cholesterol levels: results from 2 randomized, double-blind, placebo-controlled, ascending-dose phase 1 studies in healthy volunteers and hypercholesterolemic subjects on statins.

Randomized Controlled Trial

Human

2012 Nov 6

Untitled Study

Contradicting (1)