descriptive
Analysis v1
Strong Support
Top medical journals are publishing more studies that find treatments don't work now compared to 20 years ago - about 37% in 2020 versus 28% in 2000, and researchers confirmed this increase is statistically meaningful.
40
0
Evidence from Studies
Supporting (1)
40
Community contributions welcome
40
Trends of Publication of Negative Trials Over Time
Systematic Review
2025 MarThe study looked at medical journals like BMJ, JAMA, Lancet, and NEJM and found that 27.6% of published trials were negative in 2000, but 37.4% were negative in 2020 - exactly matching the claim. The difference was statistically significant (P=0.01), meaning it's unlikely to be due to chance.
Contradicting (0)
0
Community contributions welcome
No contradicting evidence found
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.