Are More Negative Drug Trials Being Published?
Trends of Publication of Negative Trials Over Time
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Researchers looked at whether more clinical trials with negative results (where the new treatment didn't work better than placebo) are being published in top medical journals over 20 years. They found more negative trials are being published now compared to 2000, but there's no clear pattern over time.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
Researchers looked at whether more clinical trials with negative results (where the new treatment didn't work better than placebo) are being published in top medical journals over 20 years. They found more negative trials are being published now compared to 2000, but there's no clear pattern over time.
Publication
Journal
Clinical Pharmacology and Therapeutics
Year
2025
Authors
B. Laviolle, Clara Locher, Jean-Sébastien Allain, Q. Le Cornu, P. Charpentier, Marie Lefebvre, Clémence Le Pape, Cyril Leven, C. Palpacuer, Clémence Pontoizeau, Eric Bellissant, F. Naudet