More visceral fat in people with psoriasis is linked to higher insulin resistance, a key factor in diabetes risk, based on statistical analysis of the data.

Scientific Claim

Higher visceral adipose tissue volume in psoriatic disease patients is associated with increased insulin resistance (HOMA-IR) in univariable analysis (beta = 74.192, p = 0.008).

Original Statement

“WB VAT: HOMA-IR univariable analysis beta = 74.192, p = 0.008”

From study:More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study is observational, so causal language is inappropriate. 'Associated with' correctly reflects the correlational nature of the finding.

Evidence from Studies

Supporting (1)

More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease

Cross-Sectional Study

Human

2023 Jun 23

Contradicting (0)

No contradicting evidence found

Source Study

More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease

Score: 42

DOI: 10.1186/s13075-023-03085-9

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