Fat around your organs links to psoriasis and health problems
More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
People with psoriasis have more fat around their organs (visceral fat) than healthy people, even if they have the same BMI. This fat is linked to worse health: more insulin resistance, higher bad cholesterol, lower good hormones, and more disease activity.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
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Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
People with psoriasis have more fat around their organs (visceral fat) than healthy people, even if they have the same BMI. This fat is linked to worse health: more insulin resistance, higher bad cholesterol, lower good hormones, and more disease activity.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 542 / 44
Evidence Score
A snapshot of a population at a single point in time. Can identify correlations and prevalence, but cannot determine the direction of cause and effect.
Publication
Authors
Blake T, Gullick NJ, Hutchinson CE, Bhalerao A, Wayte S, Weedall A, Barber TM
Related Content
Claims (10)
Visceral fat is metabolically active tissue that releases cytokines, which impair insulin sensitivity and disrupt metabolic signaling in the liver, muscles, and brain, leading to systemic metabolic dysfunction.
People with psoriasis or psoriatic arthritis have about 6% more fat around their internal organs than people without these conditions, even when they have the same body weight.
People with psoriasis or psoriatic arthritis have a higher proportion of dangerous belly fat compared to safe fat under the skin, even when their overall weight is similar to healthy people.
More visceral fat in people with psoriasis is linked to higher insulin resistance, a key factor in diabetes risk, based on statistical analysis of the data.
More visceral fat in psoriasis patients is linked to lower levels of a protective hormone called adiponectin, which helps regulate metabolism.