More visceral fat in psoriasis patients is linked to lower levels of a protective hormone called adiponectin, which helps regulate metabolism.

Scientific Claim

Higher visceral adipose tissue volume is associated with lower serum adiponectin levels (univariable beta = -30.323, p = 0.013).

Original Statement

“WB VAT: Adiponectin (per 500) univariable beta = -30.323, p = 0.013”

From study:More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease

Evidence Quality Assessment

Claim Status

appropriately stated

Study Design Support

Design supports claim

Appropriate Language Strength

association

Can only show association/correlation

Assessment Explanation

The study is observational, so 'associated with' appropriately reflects the correlational finding without implying causation.

Evidence from Studies

Supporting (1)

More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease

Cross-Sectional Study

Human

2023 Jun 23

Contradicting (0)

No contradicting evidence found

Source Study

More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease

Score: 42

DOI: 10.1186/s13075-023-03085-9

Similar Assertions

Reduction in adipose tissue volume is accompanied by increased adipocyte density, reflecting smaller adipocyte size, improved vascularization, reduced hypoxia, and decreased local inflammation.

70%