MOTS-c didn’t make mice move more, so its effects on weight and metabolism aren’t just because they were exercising more.

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13

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Evidence from Studies

Supporting (0)

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No supporting evidence found

Contradicting (1)

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Community contributions welcome

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The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Randomized Controlled Trial

Animal

2015 Mar 3

The study shows MOTS-c helps mice stay healthy and not get fat, but it never checked if the mice moved more or less, so we can't say if the health benefits are because they moved more or not.

Source Study

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Score: 13

DOI: 10.1016/j.cmet.2015.02.009

Similar Assertions

Mice given MOTS-c burned more sugar for energy and produced more body heat—even though they didn’t move around more than the control mice.

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13

77%

When mice fasted, MOTS-c levels dropped in muscles and blood but stayed the same in brain and heart.

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13

71%

Obese mice given MOTS-c had lower levels of suberate, a dicarboxylic acid, by 40% compared to untreated mice.

8

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70%