The Claim

Daily supplementation with 300 mg of Memophenol™ for 24 weeks results in a 5.90% reduction in BRIEF-A global score compared to placebo in adults aged 60–80 with mild cognitive impairment, indicating significant improvement in self-reported executive function primarily driven by metacognition.

Source: Effects of a polyphenol-rich grape and blueberry extract (Memophenol™) on cognitive function in older adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
78score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Cause and effect
1 study reviewed
In plain English

Taking 300 mg of Memophenol™ daily for 24 weeks leads to a 5.90% improvement in executive function scores on the BRIEF-A questionnaire in adults aged 60–80 with mild cognitive impairment, with the largest change seen in metacognition.

See the scientific wording

Supplementation with 300 mg daily of Memophenol™ for 24 weeks significantly improves self-reported executive function in adults aged 60–80 with mild cognitive impairment, as measured by a 5.90% reduction in BRIEF-A global score compared to placebo, primarily driven by improvements in metacognition.

Why this might work

Daily intake of polyphenols from grape and blueberry extracts reduces inflammation and oxidative damage in the brain, especially in areas responsible for planning and self-awareness. This allows brain cells to communicate more effectively, improving the ability to monitor and control thoughts and actions.

Suggested mechanismbased on 1 study

What the research says

1 study
  1. Study: Effects of a polyphenol-rich grape and blueberry extract (Memophenol™) on cognitive function in older adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study

    Older adults with mild memory issues who took a grape and blueberry extract daily for six months reported better ability to plan and organize their thoughts compared to those who took a dummy pill — and the study confirms this improvement was real and not just by chance.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

Fit Body Science verdict — we translate health claims into clear verdicts backed by peer-reviewed research.

Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.