Studies suggest that taking creatine supplements may lead to a small improvement in memory for healthy people, but the results vary widely across studies and some studies have methodological limitations.

Studies show that taking creatine supplements does not lead to measurable improvements in memory for healthy people between the ages of 11 and 31.

Powder-form creatine supplements are associated with a small but measurable improvement in memory test scores, while capsule-form creatine shows no such improvement, suggesting the physical form of the supplement may affect its impact on memory.

In older adults aged 66 to 76, taking creatine supplements is associated with a measurable improvement in memory performance compared to no supplement, but this effect is not seen in younger adults aged 11 to 31.

Taking creatine supplements might help older people (66–76) remember things better, maybe because it gives their brain more energy—but it doesn’t seem to help younger people (11–31) at all.

Taking creatine might help you remember things better when you're well-rested and calm, but it won't help if you're exhausted, sleep-deprived, or at high altitude.