People respond to weight training in wildly different ways—some grow muscles a lot, others hardly at all—and those differences between people are about 40 times bigger than the tiny differences you’d see if you trained one leg harder than the other in the same person.
Context Details
Domain
exercise_science
Population
human
Subject
Between-individual differences in muscle hypertrophy and myofibrillar protein synthesis responses to resistance training
Action
are approximately 40 times greater than
Target
differences between legs within the same person exposed to different training protocols
Intervention Details
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.
Evidence from Studies
Supporting (1)
Myofibrillar protein synthesis and muscle hypertrophy individualised responses to systematically changing resistance training variables in trained young men.
The study found that people respond to workouts in very different ways — some grow muscles a lot, others hardly at all — and those differences between people are about 40 times bigger than any tiny differences you might see between someone’s left and right leg doing different workouts.