quantitative
Analysis v1
Strong Opposition
Adults with obesity or type 2 diabetes who take a weekly 12 mg dose of retatrutide are way more likely—over 70 times more—to lose at least 15% of their body weight in less than a year compared to those taking a fake pill.
0
57
Evidence from Studies
Supporting (0)
0
Community contributions welcome
No supporting evidence found
Contradicting (1)
57
Community contributions welcome
57
Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials
Systematic Review With Meta-Analysis
Human
2025The study shows retatrutide helps people lose weight, but it doesn’t say how many people lost 15% or more, so we can’t say they were 70 times more likely to do so.
Gold Standard Evidence Needed
According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.