A super-strong weight loss medicine that works really well but can upset your tummy
Efficacy and safety of retatrutide, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: a systematic review and meta-analysis of randomized controlled trials
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study looked at a new medicine called retatrutide that helps people with extra weight or diabetes lose a lot of weight by working on three body signals at once.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 557 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Not medical advice. For informational purposes only. Always consult a healthcare professional. Terms
This study looked at a new medicine called retatrutide that helps people with extra weight or diabetes lose a lot of weight by working on three body signals at once.
No biological mechanisms were identified in this study. This may be an epidemiological, observational, or survey-based study that reports associations rather than proposing causal biological pathways.
Systematic Reviews & Meta-Analyses
Max 100Randomized Controlled Trials
Max 90Cohort Studies
Max 72Case-Control Studies
Max 58Cross-Sectional Studies
Max 44Case Reports & Case Series
Max 30Expert Opinion & Narrative Reviews
Max 557 / 100
Evidence Score
The highest quality evidence. These studies systematically search, appraise, and synthesize results from multiple individual studies, providing the most reliable summary of current knowledge.
Publication
Authors
Abdrabou Abouelmagd A, Abdelrehim AM, Bashir MN, Abdelsalam F, Marey A, Tanas Y, Abuklish DM, Belal MM
Related Content
Claims (8)
A drug called retatrutide helps people lose a lot of weight—sometimes over 70 pounds—by targeting certain hormones, but it works so well that it can cause unexpected health problems.
A drug called retatrutide probably helps people with obesity or type 2 diabetes lose about 14% of their body weight when given as a weekly shot for up to a year, and higher doses seem to lead to more weight loss.
This drug called retatrutide probably helps people with obesity or type 2 diabetes control their blood sugar better, especially if they take a higher dose.
Taking a drug called retatrutide every week for about 6 to 12 months probably helps people with obesity or type 2 diabetes lose belly fat and drop their BMI by noticeable amounts.
Taking a drug called retatrutide once a week might lower blood pressure in people with obesity or type 2 diabetes, which could help protect their heart over time.