The Claim
In humans undergoing 20 weeks of supervised resistance training, increases in muscle VDR mRNA expression are associated with gains in lean body mass, but not with changes in strength or plasma vitamin D levels, suggesting that VDR expression may serve as a biomarker of hypertrophic response independent of vitamin D status.
What the research says
Supports is higher
Support is ahead, but a single strong opposing study can change this.
These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.
When people do supervised weight training for 20 weeks, their muscles make more of a protein called VDR—and that’s linked to gaining more muscle mass, but not to getting stronger or having more vitamin D in their blood. So VDR might be a sign that muscle growth is happening, even if vitamin D levels don’t change.
See the scientific wording
In humans undergoing 20 weeks of supervised resistance training, increases in muscle VDR mRNA expression are associated with gains in lean body mass, but not with changes in strength or plasma vitamin D levels, suggesting VDR expression may serve as a biomarker of hypertrophic response independent of vitamin D status.
What the research says
1 studyStudy: Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy
When people lifted weights for 20 weeks, their muscles made more of a protein called VDR, and that meant their muscles got bigger — even if their vitamin D levels didn’t change. So VDR might be a sign your muscles are growing, not your vitamin D.
Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies
Not medical advice. For informational purposes only. Always consult a qualified healthcare professional before making health decisions.