Analysis Version
v1
History
Back to Study: Primary and secondary prevention of stroke and car...
quantitative
Analysis v1
Strong Support

Taking certain cholesterol drugs called evolocumab or alirocumab might lower the chance of having a stroke, whether you've already had heart problems or not.

38
Pro
0
Against

Evidence from Studies

Supporting (1)

38

Community contributions welcome

38

Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials.

Systematic Review With Meta-Analysis
Human
2024 Jun

The study looked at the same drugs and patients mentioned in the claim and found they do lower stroke risk, just like the claim says.

Contradicting (0)

0

Community contributions welcome

No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Primary and secondary prevention of stroke and cardiovascular events using evolocumab and alirocumab: Meta-analysis of randomized controlled trials.

Score: 38
DOI: 10.5414/CP204506

Similar Assertions

Taking a drug called evolocumab can lower the chance of having a first major heart problem by 25% in people at high risk who’ve never had a heart attack or stroke before.

100
80
87%

Taking cholesterol drugs called evolocumab or alirocumab doesn’t seem to raise your risk of bleeding in the brain — the numbers show it’s about the same as not taking them.

38
0
85%

These cholesterol drugs can cut bad cholesterol by half and help prevent heart attacks in people with heart disease, and they’re about as safe as a dummy shot—though some might get a little redness where they’re injected.

1
0
83%

For people with clogged arteries who are already taking cholesterol drugs, adding a medicine called evolocumab can help lower their chance of having a stroke.

74
0
82%

Taking a cholesterol drug called evolocumab to get really low LDL levels doesn’t seem to cause serious side effects like memory problems, diabetes, cataracts, or brain bleeds over 3 years, according to a major study.

1
0
80%