People who take cholesterol-lowering drugs and get their bad cholesterol really low don’t seem to have more side effects than those who don’t get it as low.

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Evidence from Studies

Supporting (1)

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Clinical and pathophysiological evidence supporting the safety of extremely low LDL levels-The zero-LDL hypothesis.

Narrative Review

Human

2018 Mar-Apr

The study looks at people who took cholesterol-lowering drugs and had very low LDL levels, just like in the claim, and found they didn’t have more side effects.

Contradicting (0)

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Clinical and pathophysiological evidence supporting the safety of extremely low LDL levels-The zero-LDL hypothesis.

Score: 1

DOI: 10.1016/j.jacl.2017.12.018

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