A study found that adults who took a supplement called Rejuvant® (containing alpha-ketoglutarate and vitamins) for about 7 months had their biological age reduced by an average of 8 years, as measured by a DNA test called TruAge.

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Evidence from Studies

Supporting (1)

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Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test

Cohort Study

Human

2021 Nov 30

The study tested the exact same thing as the claim: people taking Rejuvant® for about 7 months and measuring their biological age with a DNA methylation test. The study found an 8-year reduction in biological age, which matches what the claim says exactly.

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According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test

Score: 39

DOI: 10.18632/aging.203736

Similar Assertions

Thirteen people who didn't change anything about their lifestyle except taking a supplement called Rejuvant® for about 7 months saw their biological age drop by nearly 8 years on average.

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78%

Men taking Rejuvant® for 4-10 months looked about 8.4 years younger biologically, while women looked about 7 years younger on average.

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78%

Taking Rejuvant® supplements for longer periods doesn't necessarily mean you'll get more benefits in terms of reducing your biological age - the effect seems to max out after about 7 months.

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77%

A company studied their supplement Rejuvant® and found that 40 out of 42 people (almost everyone) became biologically younger after taking it for several months.

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76%

People who looked older than their actual age (based on biological markers) saw bigger improvements in their biological age after taking Rejuvant® supplement, meaning the supplement might work better for people who are aging faster.

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70%