The Claim

In adults with chronic tinnitus, elevated baseline stress (PSQ index ≥0.45) is associated with greater improvement in tinnitus loudness and annoyance following 24 weeks of treatment with Ginkgo biloba extract EGb 761®.

Source: Ginkgo biloba Extract EGb 761® in Patients with Chronic Tinnitus: Treatment Effects and Effect Modifiers

What the research says

Supports is higher

Support is ahead, but a single strong opposing study can change this.

Supports
62score
Challenges
0score

These are independent scores, not a percentage. Higher-grade studies count more, so a single strong opposing study can outweigh several weaker ones.

Correlation
1 study reviewed
In plain English

Adults with chronic tinnitus who have high baseline stress levels show greater reductions in tinnitus loudness and annoyance after 24 weeks of taking Ginkgo biloba extract EGb 761® compared to those with lower stress levels.

See the scientific wording

In adults with chronic tinnitus, elevated baseline stress (PSQ index ≥0.45) is associated with greater improvement in tinnitus loudness and annoyance following 24 weeks of treatment with Ginkgo biloba extract EGb 761®, with statistically significant differences observed in these specific outcomes.

Why this might work

When stress is high, the brain's stress systems are overactive and disrupt how the hearing system filters out background noise. Ginkgo biloba improves blood flow to the inner ear and calms overactive brain circuits by balancing key chemicals like dopamine and acetylcholine. This restores the brain's ability to suppress false hearing signals, making tinnitus quieter and less annoying — especially when stress was high to begin with.

Supported mechanismbased on 1 study

What the research says

1 study
  1. Study: Ginkgo biloba Extract EGb 761® in Patients with Chronic Tinnitus: Treatment Effects and Effect Modifiers

    People with chronic tinnitus who were more stressed before starting Ginkgo biloba treatment tended to feel much better after six months than less stressed people. The study found stress was linked to better results.

Score breakdown, mechanism chain, raw evidence, ideal studies needed & 1 supporting studies

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