People with this inherited high-cholesterol condition who also have metabolic syndrome are almost five times more likely to die from any cause over the next 30 years.

People with a genetic condition that gives them high cholesterol are much more likely to have a heart attack or stroke within 10 years if they also have metabolic syndrome — even if their cholesterol is being managed.

If someone has high cholesterol from birth and also has metabolic syndrome, they’re nearly five times more likely to have a heart attack, stroke, or need a heart procedure within 10 years.

Young adults with a genetic cholesterol problem are more likely to have heart artery plaque than their peers without it — more than half of them do, compared to about one in five others.

Adult males with metabolic syndrome based on National Cholesterol Education Program guidelines have a 73% higher chance of silent heart disease compared to those without, according to the study. This finding is from the abstract summary - full study details were not available