For people with type 2 diabetes and healthy kidneys, taking a weekly exenatide shot might slightly lower the risk of heart problems or dying, but the evidence isn't strong and hasn't been fully checked for other factors.

A weekly diabetes shot called exenatide doesn’t seem to lower the risk of serious kidney problems in adults with type 2 diabetes when looking at the raw data. But when researchers adjusted the numbers, it showed a small benefit when including a wider range of kidney issues, like high protein in the urine.

Taking a weekly exenatide shot doesn’t really change how well your kidneys are working if you have type 2 diabetes — the numbers stayed about the same over time.

Taking a weekly diabetes shot called exenatide doesn’t seem to lower the risk of a specific type of kidney problem in adults with type 2 diabetes — the numbers don’t show a clear benefit.

Taking a weekly diabetes shot called exenatide may help lower the chance of dying or ending up in the hospital with heart failure for people with type 2 diabetes.

If you have type 2 diabetes and already have heart failure, the weekly diabetes shot exenatide might not help you live longer or keep you out of the hospital for heart problems. But if your heart is healthy, it could lower your risk of dying by 21%.