If postmenopausal women using estrogen patches also take a supplement called DIM, it might change how their body processes estrogen—lowering some types linked to higher risk and raising others that may be safer.

Taking DIM supplements might help boost a certain healthy estrogen process in postmenopausal women who use estrogen patches — one study found their urine had 24% more of a specific marker linked to this process.

Taking a supplement called DIM every day for a month doesn’t seem to change a certain hormone balance in premenopausal Mexican women that’s linked to lower breast cancer risk — but there might be a slight improvement a month after stopping.

Taking DIM supplements might lower a certain estrogen byproduct in the urine of postmenopausal women who use estrogen patches — one study found levels were 22% lower in those taking DIM.

Taking DIM supplements might lower estrogen levels in postmenopausal women who use estrogen patches — one study found their urine had less estrogen when taking DIM.

Taking a daily supplement with certain plant compounds might help your body process estrogen in a healthier way, which could lower the risk of some hormone-related cancers in women, whether or not they’ve gone through menopause.