Giving a supplement called nicotinamide riboside to rats on a high-fat diet might help them absorb more fat and energy, but it doesn’t seem to do anything if they’re eating regular food.

45

Pro

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Against

Evidence from Studies

Supporting (1)

45

Community contributions welcome

45

Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

Randomized Controlled Trial

Human & Animal

2023 Apr 3

The study gave rats a supplement called nicotinamide riboside and found it made them absorb more fat and energy—but only if they were eating a high-fat diet, just like the claim says.

Contradicting (0)

0

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No contradicting evidence found

Gold Standard Evidence Needed

According to GRADE and EBM methodology, here is what ideal scientific evidence would look like to definitively prove or disprove this specific claim, ordered from strongest to weakest evidence.

Source Study

Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

Score: 45

DOI: 10.1038/s41514-023-00106-4

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