Taking a supplement called nicotinamide riboside for six weeks might change how certain genes work in people with moderate to severe kidney disease, possibly helping with energy and metabolism.

Taking a supplement called nicotinamide riboside for six weeks might change how genes work in the blood of people with moderate to severe kidney disease, possibly affecting how the body handles sugar, fat, and the immune system.

Taking a supplement called nicotinamide riboside for six weeks might help immune cells in people with kidney disease work better by boosting their energy levels.

In people with moderate to severe kidney disease, taking either nicotinamide riboside or coenzyme Q10 for six weeks seems to change how certain genes work in the blood — one affects energy and fat processing, while the other influences immunity and stress, suggesting they work in different ways.

Taking a supplement called nicotinamide riboside for six weeks might help immune cells in people with serious kidney disease work better by boosting their energy levels.

In people with moderate to severe kidney disease, taking 1000 mg of nicotinamide riboside daily for six weeks may boost energy in immune cells, but the same doesn’t happen with a high dose of CoQ10.