Taking a supplement called nicotinamide riboside for six weeks might change how genes work in the blood of people with moderate to severe kidney disease, possibly affecting how the body handles sugar, fat, and the immune system.

Taking a supplement called nicotinamide riboside for six weeks might change how certain genes work in people with moderate to severe kidney disease, possibly helping with energy and metabolism.

In people with moderate to severe kidney disease, taking either nicotinamide riboside or coenzyme Q10 for six weeks seems to change how certain genes work in the blood — one affects energy and fat processing, while the other influences immunity and stress, suggesting they work in different ways.

Taking a supplement called nicotinamide riboside for six weeks might help immune cells in people with kidney disease work better by boosting their energy levels.

Taking a supplement called nicotinamide riboside every day for six weeks might boost a protein in the blood that affects the immune system in people with moderate to severe kidney disease — but we don’t know yet if that change actually helps or matters for their health.

Taking a supplement called nicotinamide riboside every day for six weeks might help reduce harmful stress in the body for adults with moderate to severe kidney disease.